Why ADOMEDS®?

• Can be used by patients with mildly symptomatic depression and the ones diagnosed with MDD. 1, 2, 5 & 7
• Can be used as an adjunctive agent along with conventional antidepressants for MDD. 2, 4, 5 & 9
• Beneficial for treatment-resistant patients or the ones who are unable to tolerate the side effects. 2, 4
• Promotes sexual function such as libido and erection. 10
• Reduces sexual dysfunction caused by antidepressants. 10, 11
• Shows promise in treatment of neuropsychiatric diseases, such as fibromyalgia. 2, 5
• Shows positive response on mood in neurological disorders, such as epilepsy. 12
• Helps CNS (re-)myelination in neurodegenerative diseases, such as multiple sclerosis(MS). 13
• Generally well-tolerated with less adverse effects and rapid onset of action. 2, 4, 5 & 9

Abbreviated Prescribing Information
ADOMEDS®
S-Adenosyl-L-Methionine (SAM-e), Oral Capsules 400mg
Other ingredients: Microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate.
Indication: Mild depression, major depressive disorder (MDD), sexual dysfunction, fibromyalgia, MS.
Dosing: 400mg ADOMEDS® capsule can be used twice per day. Depending on clinical response, ADOMEDS® dose can be increased to 1600 mg per day. ADOMEDS® should be taken on empty stomach, i.e., one hour before or two hours after meals. It is better to take ADOMEDS® in two or three divided doses with meals.
Contraindication: Allergic to any ingredient in ADOMEDS®. Should be avoided in patients using Levodopa.
Side effects: Side effects that have been reported may include mild gastrointestinal upset (e.g. stomach pain, nausea, diarrhea, and flatulence), anxiety, hypomania and insomnia.
Due to above facts, you should not take this supplement at night.
Pregnancy & Lactation: ADOMEDS® should only be used by pregnant woman under a physician’s supervision. Nursing mothers should avoid SAM-e supplementation.
Warning: Patients with bipolar disorder should not take ADOMEDS® without concomitant administration of mood stabilizers coupled with clinical monitoring.
ADOMEDS® is a product of Ashbal Chemi using API (Adomix®) by Gnosis, Italy